While Cognitive Behavioral Therapy (CBT) remains the dominant foundation for many digital interventions, the sector actively deploys and explores a broader spectrum of therapeutic modalities to address diverse clinical needs. Mindfulness-Based Interventions (MBIs), often delivered via self-guided mobile apps, have seen widespread adoption, frequently marketed as "well-being enhancement" tools. These apps provide guided meditations and stress-reduction exercises and have shown effectiveness in improving general psychological well-being.

Furthermore, platforms are starting to incorporate or augment care with elements of other proven therapies, such as modules based on Dialectical Behavior Therapy (DBT) skills training, which are critical for emotion regulation and interpersonal effectiveness. Digital tools also serve as powerful adjuncts to in-person care, facilitating remote symptom monitoring and offering psychoeducation. The shift toward these specialized and combined modalities is enhancing the sector's utility for managing complex and co-occurring mental and behavioral disorders, a trend visible across the service spectrum of the Digital Mental Health Market, detailed in treatment modality studies, such as the Digital Mental Health Market Global Outlook.